
The practice of immunization dates back hundreds of years.
- Buddhist monks drank snake venom to confer immunity to snake bite and variolation (smearing of a skin tear with cowpox to confer immunity to smallpox) was practiced in 17th century China.
- Edward Jenner is considered the founder of vaccinology in the West in 1796, after he inoculated a 13 year-old-boy with vaccinia virus (cowpox), and demonstrated immunity to smallpox.
- In 1798, the first smallpox vaccine was developed.
- the right of government to impose vaccines was established by the Supreme Court in Jacobson v. Massachusetts. In a 7-to-2 ruling, the Court said Cambridge, Massachusetts could require all adults to be vaccinated against smallpox.
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